Full Cast — Big Mouth (2017–2025)

Nick Kroll

Nick Birch / Maury the Hormone Monster / Coach Steve / Lola Skumpy / Rick the Hormone Monster (voice)

John Mulaney

Andrew Glouberman (voice)

Jessi Klein

Jessi Glaser (voice)

Jason Mantzoukas

Jay Bilzerian (voice)

Maya Rudolph

Diane Birch / Connie the Hormone Monstress (voice)

Fred Armisen

Elliot Birch (voice)

Jordan Peele

Ghost of Duke Ellington (voice)

Andrew Rannells

Matthew (voice) / Leander / Matthew MacDell (voice)

Jenny Slate

Missy Foreman-Greenwald (voice) / Pharmacist / Caitlin (voice)

Joe Wengert

Caleb / Dot #3 / Leore Paulblart (voice) / Caleb / Go-Gurt Thief / Teacher (voice) / Caleb (voice) / Caleb / Pornscape Residents (voice) / Steven Tyler Glade Plug-In / Zombie (voice) / Caleb / Lump Humpman (voice) / Caleb / Go-Gurt Burglar (voice) / Stan the Hormone Monster +8 more

Ayo Edebiri

Missy Foreman-Greenwald (voice) / Missy Foreman-Greenwald / Mosaic Missy (voice)

June Diane Raphael

Devin (voice)

Richard Kind

Marty Glouberman (voice)

Paula Pell

Barbara Glouberman / Bubbe (voice) / Barbara Glouberman / Lola's Couch Pillow (voice) / Barbara Glouberman (voice) / (voice)

Neil Casey

Detective Dumont (voice) / Lars / Boy (voice) / Lars / Detective Dumont / Pornscape Residents (voice) / Lars / Jew Penis (voice) / Lars / Rewind Shirt Kid (voice) / (voice) / Detective Dumont / Lars (voice) / Lars / Detective Dumont (voice) / Lars (voice) / Detective Dumont / D.N. Ape (voice)

Jessica Chaffin

Shannon Glaser (voice) / Shannon Glaser / Grace / Intellect Sphinx (voice)

Jon Daly

Judd Birch / Pumbaa (voice) / Judd Birch (voice) / Garrison Keillor / Magician #1 (voice)

Jak Knight

DeVon (voice) / DeVon / DeVon / Gina's Brother #2 (voice) / Tall Guy (voice)

Chelsea Peretti

Monica Foreman-Greenwald (voice) / Diaphragm (voice) / Cellsea (voice)

Seth Morris

Ninth Grader (voice) / Greg Glaser (voice) / (voice)

Mark Rivers

Man #2 / Penis Worms (voice) / Maury's Backup Singer (voice) / Siamese Twin #1 (voice) / Backup Singer (voice) / Vendor (voice) / Michael Stipe Tampon (voice) / (voice) / Ghost of David Bowie (voice)

Gil Ozeri

The Ponytail Killer / Pornscape Residents (voice) / Wiggles (voice) / Jew Fishman (voice) / Brad (voice) / (voice) / Man #1 / Dot #2 (voice)

Nathan Fillion

Nathan Fillion (voice)

Kat Dennings

Leah Birch (voice) / Leah Birch / Lorraine the Hormone Monstress (voice)

Gina Rodriguez

Gina Alvarez / Gina Parrot (voice) / Gina Alvarez (voice)

David Thewlis

Lionel St. Swithens (voice) / Actor (voice) / Shame Wizard (voice)

Thandiwe Newton

Mona (voice)

Heather Lawless

Jenna Bilzerian (voice)

Maria Bamford

Tito Taylor Thomas (voice) / Tito the Anxiety Mosquito (voice)

Brandon Kyle Goodman

Walter the Lovebug (voice) / Walter (voice)

Mark Duplass

Val Bilzerian (voice)

Whitmer Thomas

Camus Boy / Weed Boy / Sad Boy #1 (voice) / Camden (voice)

Paul Scheer

Kurt Bilzerian (voice)

Ali Wong

Ali (voice)

Zachary Quinto

Aiden (voice)

Stephanie Beatriz

Lulu (voice)

Emily Altman

Milk (voice) / Vicky (voice) / (voice) / Olivia / Filmstrip Narrator (voice)

Chloe Fineman

Leah Birch (voice)

Rob Huebel

Mr. Lizer (voice)

Natasha Lyonne

Suzette (voice) / Ms. Dunn (voice)

Gary Cole

Andrew's Father (voice) / Edward MacDell (voice) / Matthew's Father (voice)

Jean Smart

Depression Kitty (voice)

Jack McBrayer

Pubic Hair #1 (voice) / Jack (voice)

John Gemberling

Security Guard / Bus Driver's Son (voice) / Tyler the Hormone Monster (voice) / Tyler the Hormone Monster / Dot #1 (voice)

Craig Robinson

End Credits Singer (voice) / Harvey Brooks (voice) / Craig (voice) / Pubic Hair #2 (voice)

Michaela Watkins

Cantor Dina Reznick (voice)

Fran Gillespie

Samira (voice) / Girl (voice) / Maddie the American Girl Doll / Choir Girl (voice) / (voice)

Kristen Bell

Pam the Pillow (voice) / Uninterested Girl (voice)

Ashley London

Skank (voice) / (voice) / Kitty / DNA Expert / Pornscape Residents (voice) / The Virgin Mary / Waitress (voice)

Zach Woods

Daniel (voice) / Sock (voice)

Rosa Salazar

Ms. Benitez (voice)

Quinta Brunson

Girl (voice) / Quinta (voice)

Ayden Mayeri

Gabrielle (voice) / Gabrielle / Mellon Ball / Honeydew (voice) / Gabrielle / Sad Boy #2 (voice) / Gabrielle / Freshman (voice)

Andy Daly

Ghost of Harry Houdini (voice) / Dr. Wendy Engle (voice) / Dr. Wendy Engle / Motel Pillow #1 (voice)

Bobby Cannavale

Gavin the Hormone Monster (voice) / Nick's Agent (voice) / Gavin (voice)

John Oliver

Harry (voice)

Seth Rogen

Seth Goldberg (voice)

Lena Waithe

Lena (voice)

Julie White

Kimberly (voice) / Kimberly MacDell (voice)

Sterling K. Brown

Michael Angelo (voice)

Crissy Guerrero

(voice)

Kristen Wiig

Jessi's Vagina (voice)

Megan Thee Stallion

Megan the(e?) Hormone Monstress (voice)

Patrick Page

Dread (voice)

Juliet Mills

Rita St. Swithens (voice)

Ileen Goldsmith

(voice) / Jessi Glaser - singing double / Judd's Girlfriend (voice)

Brendan McCreary

Freddie Mercury (singing voice) / Ghost of Freddie Mercury (voice)

Carlos Alazraqui

Gustavo (voice)

Julie Klausner

Cherry Marashina (voice)

Chris Redd

(voice)

Josie Totah

Natalie (voice)

Joel Kim Booster

Charles Lu (voice)

Judd Hirsch

Lewis Glouberman (voice)

Beck Bennett

Owen (voice)

Billy Porter

Ocean (voice)

J Valerione

B-High Qee-Choi Member (voice)

Keke Palmer

Rochelle the Hate Worm (voice)

Aidy Bryant

Emmy (voice)

Rosie Perez

Petra (voice)

Mitra Jouhari