Full Cast — Masters of Sex (2013–2016)

Michael Sheen

William Masters

Lizzy Caplan

Virginia Johnson

Caitlin FitzGerald

Libby Masters

Annaleigh Ashford

Betty DiMello

Teddy Sears

Austin Langham

Kevin Christy

Lester Linden

Beau Bridges

Barton Scully

Heléne Yorke

Jane Martin

Nicholas D'Agosto

Ethan Haas

Julianne Nicholson

Dr. Lillian DePaul

Kayla Madison

Tessa Johnson

Jaeden Martell

Johnny Masters

Josh Charles

Dan Logan

Isabelle Fuhrman

Tessa Johnson

Cole Sand

Henry Johnson

Allison Janney

Margaret Scully

Benjamin Koldyke

Paul Edley

Jeremy Strong

Art Dreesen

Betty Gilpin

Nancy Leveau

Rose McIver

Vivian Scully

Jack Laufer

Herb Spleeb

Ann Dowd

Estabrooks Masters

Betsy Brandt

Barbara Sanderson

Artemis Pebdani

Flo Packer

Jocko Sims

Robert Franklin

Sarah Silverman

Helen Schiff

Danny Jacobs

Bob Drag

David Walton

Bram Keller

Nick Clifford

Guy

Greg Grunberg

Gene Moretti

Mather Zickel

George Johnson

Michael O'Keefe

Harry Eshelman

Christopher Clausi

Patron (uncredited) / Journalist (uncredited) / Bar Single (uncredited) / Party Guest (uncredited)

Garrett M. Brown

Chancellor Fitzhugh

Colin Woodell

Ronald Sturgis

Niecy Nash-Betts

Louise Bell

Alyvia Alyn Lind

Jenny Masters

Jorie Stern

Nurse (uncredited)

Finn Wittrock

Dale

Keke Palmer

Coral

Kandis Fay

Pam

Emily Kinney

Nora Everett

John Billingsley

Dr. Lloyd Madden

Frederick Keeve

AA Member (uncredited) / Client (uncredited)

Frances Fisher

Edna Eshelman

Susie Schelling

OR Nurse / Scrub Nurse

Evan Arnold

Dr. Ditmer

Danny Huston

Dr. Douglas Greathouse

Christina Cannarella

Maternity Nurse / ER Nurse / Delivery Nurse

Courtney B. Vance

Dr. Charles Hendricks

Elizabeth Bogush

Elise Langham

Barry Watson

Shelley Decklin

Alex Wyse

Elliot

Marin Ireland

Pauline Masters

Christian Borle

Frank Masters

Adam Arkin

Shep Tally

Elijah Rock

Manny

Nick Gillie

Glenn

Susan May Pratt

Joy Edley

Cary Huff

Public Defender (uncredited) / Doctor (uncredited)

Blake Morgan Ferris

Dennis

Kevin Fonteyne

Matt

Brian Howe

Sam Duncan

Rob Benedict

Jonathan Laurents

John Gleeson Connolly

Hugh Hefner

Rondi Reed

Edith Schiff

Charles Shaughnessy

Charles Clavermore

Joanna Canton

Cherlyn Green

Kelli O'Hara

Dody

Nicholle Tom

Maureen

Sara Rae Foster

Dottie

Ellen Wroe

Ginger

William Nicol

Assistant Doctor / Operating Doctor #2

Alan Ruck

Psychiatrist

Logan Donovan

Travis Banks

Adam Silver

Tim Deasy

Joan Severance

Leona

Mary Passeri

Jean Richards

Marlane Barnes

Gladys

Jennifer Holloway

Ramona

Anne Griffin

Kathleen

James Eckhouse

Dr. Chuck Ingram

Tim Ransom

Dr. Rish

Kyla Deaver

Katie Langham

Will Jennings

Sam Langham

Rya Kihlstedt

Tatti Greathouse

Rebecca Kessler

Maternity Ward Candy Striper (uncredited)

Johnny Sneed

Al

Maitely Weismann

Mariel

Benjamin Pitz

Football Referee (uncredited) / Italian Restaurant Waiter (uncredited)

Katie Parker

Bernadette

John Brugal

Kyle

Eve Gordon

Judith

Tate Donovan

Graham Pennington

Julie Ann Emery

Jo

Daniel Rubiano

Thomas

Frank Clem

Zookeeper Steve / Steve

Toni French

Restaurant Patron (uncredited) / Washington University Attendee (uncredited)

Dennis Cockrum

Francis Masters

Rich Sommer

Dale Connolly

Erin Karpluk

Darleen Connolly

Judy Greer

Alice Logan

Ashley Zukerman

Gary Bucksey

Amanda Quaid

Fran Bucksey

Joel Brooks

Mr. Schiff

Rick Peters

Nathan

Lisa Banes

Nina Clavermore

Aaron Abrams

Randy

Corey Reynolds

James Bell

Caiden Milick

Howie Masters

Madeline Ruskin

Holly (uncredited)