Full Cast — Roseanne (1988–2018)

Roseanne Barr

Roseanne Conner

John Goodman

Dan Conner

Sara Gilbert

Darlene Conner

Michael Fishman

D.J. Conner

Laurie Metcalf

Jackie Harris

Alicia Goranson

Becky Conner

Johnny Galecki

David Healy

Sarah Chalke

Becky Conner

Glenn Quinn

Mark Healy

Estelle Parsons

Beverly Harris

Natalie West

Crystal Anderson

Martin Mull

Leon Carp

Michael O'Keefe

Fred

Sandra Bernhard

Nancy

Tom Arnold

Arnie Thomas

Bonnie Bramlett

James Pickens Jr.

Chuck Mitchell

George Clooney

Shelley Winters

Nana Mary

Ames McNamara

Mark Conner-Healy

Jayden Rey

Mary Conner

Emma Kenney

Harris Conner-Healy

Ned Beatty

Ed Conner

Matt Roth

Danielle Harris

Molly Tilden

Brian Kerwin

Charlayne Woodard

Wings Hauser

Lori Tan Chinn

Iris

Mara Hobel

Joseph Gordon-Levitt

George

Stephen Dorff

Jared Rushton

Melora Walters

Fred Willard

Debra Mooney

Stan Freberg

Carl Franklin

Colleen Camp

Kathleen Freeman

Jay O. Sanders

Ziggy

John Randolph

Doug Fieger

Liz Georges

Elizabeth Franz

William Sadler

Heather Matarazzo

Michael Des Barres

Lee Garlington

Dan Butler

Luke Edwards

Kathryn Joosten

Morgan Fairchild

Mariel Hemingway

Sharon

Danny Masterson

Jimmy

Michael Dempsey

Tristan Tait

Phil Leeds

Grandmama Lily

Jeremy Roberts

Mo Gaffney

Astrid Wentworth

Stella Butler

Nurse Stella

Zoe Perry

Young Jackie / Little Jackie