Full Cast — The Jetsons (1962–1987)
George O'Hanlon
George Jetson (voice)
Penny Singleton
Jane Jetson (voice)
Daws Butler
Elroy Jetson (voice)
Janet Waldo
Judy Jetson (voice)
Jean Vander Pyl
Rosie (voice)
Don Messick
Astro (voice)
Mel Blanc
Cosmo S. Spacely (voice)
Frank Welker
Orbitty (voice)
Howard Morris
Jet Screamer (voice) / Emcee (voice) / Mr. Tweeter (voice) / Harlan (voice) / Nimbus the Great / George's Conscience / Willie (voice) / Montague Jetson (voice) / Boppo Crushstar / CB (voice) / Bus Driver (voice)
Allan Melvin
Mangler Mars (voice) / Mr. Spendwell / Construction Worker (voice) / Jacob Marsley / Ghost of Christmas Present (voice) / Solareenie (voice)
Shepard Menken
Mugsy Megatron / Microbe (voice) / (voice) / Nimbly (voice)
Dick Beals
Arthur Spacely (voice) (uncredited) / (voice) / Arthur Spacely (voice)
John Stephenson
Gary Gammaray (voice) / Commissioner / DWMR Officer (voice) / Dr. Scarem (voice)
Barry Gordon
Sneak (voice) / Tiny Terror / Betting Machine (voice) / Mechanic (voice)
Hal Smith
(voice) / Beta Ranch Manager (voice)
Joan Gardner
Helen (voice) (uncredited) / (voice)
Selma Diamond
Di-Di (voice)
Frank Nelson
Robot Dance Instructor (voice) / Ralph (voice)
Sonny Melendrez
Mr. Rocket (voice) / Gus Guesser - Game Show Host (voice)
Brenda Vaccaro
Di-Di (voice)