Full Cast — Watson (2025–2026)

Morris Chestnut

Dr. John Watson

Eve Harlow

Dr. Ingrid Derian

Peter Mark Kendall

Dr. Stephens Croft / Dr. Adam Croft

Inga Schlingmann

Dr. Sasha Lubbock

Ritchie Coster

Shinwell Johnson

Rochelle Aytes

Dr. Mary Morstan

Riley Orr

Glen/Croft Twin / Croft Twin

Robert Carlyle

Sherlock Holmes

Rachel Hayward

Detective Lestrade

John Cassini

Dr. Ivan Ferry

Noah Mills

Beck Wythe

Karen Robinson

Brenda the Battle Axe

Amanda Crew

Lauren Confalone / Lauren

Tika Sumpter

Dr. Laila Bynum

Kacey Rohl

The Rep

Louriza Tronco

Nurse Reyes

Kalyn Miles

Nurse Andrews / ER Nurse Andrews

Vincent Gale

Mycroft Holmes

Марго Бингхэм

Nurse Carlin DaCosta

Alejandra Chavarria

O.R. Nurse

Andrew Dobbie

Croft Twin

Randall Park

Moriarty

Hampton Fluker

Dr. Isaac Niles

Bethany Brown

Devin Chaplin

Sofie Kane

Porsche

Tommy O'Brien

Zach

Kareem Malcolm

Dr. Marcus

Alan Ramon Ward

Nurse Jace

Nat Faxon

Hobie McSorley

Kiera Allen

Gigi Grigoryan

Shalyn Ferdinand

ER Doctor Leela / Dr. Leela

Alexandra Khan-Anselmo

Nurse Ward / Dorothy Ward

Tzi Ma

Uncle Jun

Alexandria Maillot

OR Nurse Petra

Margot Bingham

Nurse Carlin DaCosta

Hannah Henney

Ultrasound Tech Jahna / X-ray Tech Jahna

Maggie Ma

Nurse Han / Nadine

C.J. Lindsey

Josh Gibson

Helen Cespedes

Dr. Tabitha Malena